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Product descriptionSafety INDICATIONS Fluoxetine is used for treating premenstrual dysphoric disorder (PMDD), a severe form of premenstrual syndrome. Fluoxetine is a selective serotonin reuptake inhibitor (SSRI). It works by restoring the balance of serotonin, a natural substance in the brain, which helps to improve mood.
Pharmachologic effect
Antidepressant group of selective serotonin reuptake inhibitors. Timoanalepticheskim and has a stimulating effect.
Selectively blocking reverse neuronal uptake of serotonin (5 HT) neurotransmission in the neurons of the central nervous system. Inhibition of reuptake of serotonin leads to increasing the concentration of the neurotransmitter in the synaptic cleft, and amplifies its effect on ppolongiruet postsinapticheskie petseptopnyeuchastki. By increasing serotonergic transmission, the mechanism of the negative membrane due fluoxetine inhibits neurotransmitter exchange. With prolonged use of fluoxetine inhibits the activity of 5-HT1 receptors. It has little effect on the reuptake of norepinephrine and dopamine.It has no direct effect on serotonin, m-cholinergic, histamine H1, and adrenergic receptors alpha. Unlike most antidepressants cause a decrease in postsynaptic activity of beta-adrenergic receptors.Effective with endogenous depression and obsessive-compulsive disorders. Has anorectic action can cause weight loss. It does not cause orthostatic hypotension, sedation, nekardiotoksichen. Persistent clinical effect occurs within 1-2 weeks of treatment.
Pharmacokinetics
When administered drug is well absorbed from the gastrointestinal tract (up to 95% of the dose), the use of food slows the absorption of fluoxetine significantly. Cmax plasma levels are reached in 6-8 hours. The bioavailability after oral administration of fluoxetine is greater than 60%. The drug was well accumulates in the tissues, readily crosses the blood-brain barrier, binding to plasma proteins is 90%.It is metabolized in the liver by demethylation to the active metabolite nor fluoxetine and several unidentified metabolites. Excreted by the kidneys as metabolites (80%) and bowel (15%), mainly in the form of glucuronides.T1 / 2 fluoxetine after reaching equilibrium concentration in plasma is about 4-6 days. T1 / 2 of the active metabolite, norfluoxetine with single dose and after reaching equilibrium concentration in the plasma is from 4 to 16 days. In patients with hepatic failure half-life of fluoxetine and norfluoxetine is prolonged.
Dosage
The drug is taken orally, at any time, regardless of the meal.
doldrums The initial dose is 20 mg 1 time / day in the first half of the day, regardless of meals. If necessary, the dose may be increased to 40-60 mg / day, divided into 2-3 doses (20mg / day weekly). The maximum daily dose – 80 mg 2-3 reception.The recommended dose is 20-60 mg / day.
Friend Interaktions
You can not use the drug simultaneously with MAO inhibitors, including antidepressants – MAO inhibitors; furazolidone, procarbazine, selegiline, and tryptophan (a precursor of serotonin), as may develop serotonin syndrome, which manifests itself in confusion, hypomania, agitation, convulsions, dysarthria, hypertensive crisis, chills, tremors, nausea, vomiting, diarrhea.
Conditions and terms
In a dry, dark place at a temperature no higher than 25 ° C. Keep out of the reach of children. Shelf life – 3 years.
Indications.
– Depression of various origins;
– Obsessive-compulsive disorder;
– Bulimic neurosis.
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Before you purchase Generic domperidone without prescription, you should weigh all the cons and pros of such treatment. Your doctor should conclude if Motilium pills present any risks for your health. In particular, you should know whether you have an allergy to the active ingredient or any other types of allergic reactions related to food, your lifestyle, etc. Moreover, you should discuss your current medical problems with the medical specialist. You should tell your doctor if you have any of the following signs and symptoms:
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Motilium can cause not only desired medical effects, but also side effects which are different in their strength and duration. It’s vitally important to react to serious side effects by seeking immediate medical attention.
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排卵誘発剤（クロミフェン）は、非ステロイド性不妊薬です。これは、排卵（卵巣からの卵子の放出）を刺激するために必要なホルモンを解放する下垂体が発生します。
クロミッドは自然排卵の発生防止（例えば多嚢胞性卵巣症候群など）特定の医療条件を持つ女性で排卵を引き起こすために使用されます。
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Clomid (clomifene) è un farmaco di fertilità non steroideo. Essa provoca la ghiandola pituitaria a rilasciare gli ormoni necessari per stimolare l’ovulazione (il rilascio di un uovo dalle ovaie).
Clomid è usato per indurre l’ovulazione nelle donne con determinate condizioni mediche (come la sindrome dell’ovaio policistico) che impediscono naturalmente allo dell’ovulazione.
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Clomid (clomiphene) punika medicine kesuburan non-steroid. Iku nimbulaké kelenjar hipofisis dipedhot hormon needed kanggo ngrangsang ovulation (release saka endhog saka ovary).
Clomid digunakake kanggo nimbulaké ovulation ing wanita kanthi kahanan mèdhis tartamtu (kayata sindrom ovary disease) sing nyegah alami ovulation.
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Clomid (clomifène) est un médicament de fertilité non stéroïdien. Il provoque l’hypophyse à libérer des hormones nécessaires pour stimuler l’ovulation (libération d’un ovule par l’ovaire).
Clomid est utilisé pour provoquer l’ovulation chez les femmes atteintes de certaines maladies (comme le syndrome des ovaires polykystiques) qui empêchent l’ovulation se produisant naturellement.
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克罗米芬（克罗米酚）是一种非甾体类生育药。它会导致脑下垂体释放刺激排卵（卵的从卵巢中释放）所需的激素。
克罗米芬用于使排卵的妇女与某些健康状况（如多囊卵巢综合征），该防止天然存在的排卵。
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克羅米芬（克羅米酚）是一種非甾體類生育藥。它會導致腦下垂體釋放刺激排卵（卵的從卵巢中釋放）所需的激素。
克羅米芬用於使排卵的婦女與某些健康狀況（如多囊卵巢綜合徵），該防止天然存在的排卵。
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Τι είναι Clomid;
Clomid (clomiphene) είναι ένα μη στεροειδές φάρμακο γονιμότητας. Προκαλεί την υπόφυση για την απελευθέρωση ορμονών που απαιτούνται για την πρόκληση ωοθυλακιορρηξίας (απελευθέρωση ενός ωαρίου από την ωοθήκη).
Clomid χρησιμοποιείται για να προκαλέσει ωορρηξία σε γυναίκες με ορισμένες ιατρικές συνθήκες (όπως το σύνδρομο πολυκυστικών ωοθηκών) που εμποδίζουν φυσικά ωορρηξία.
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¿Qué es Clomid?
Clomid (clomifeno) es un medicamento de fertilidad no esteroideo. Se hace que la glándula pituitaria para que libere las hormonas necesarias para estimular la ovulación (la liberación de un óvulo del ovario).
Clomid se usa para provocar la ovulación en mujeres con ciertas condiciones médicas (como el síndrome de ovario poliquístico) que impiden que ocurren naturalmente ovulación.
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Clomid (klomifen) är ett icke-steroidalt fertilitet medicin. Det orsakar hypofysen att frigöra hormoner som behövs för att stimulera ägglossning (frisläppandet av ett ägg från äggstocken).
Clomid används för att åstadkomma ägglossning hos kvinnor med vissa medicinska tillstånd (t.ex. polycystiskt ovariesyndrom) som förhindrar naturligt förekommande ägglossning.
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Clomid (clomiphene) ni yasiyo ya steroidal uzazi dawa. Ni sababu tezi ya kutolewa homoni zinahitajika ili kuchochea ovulation (kutolewa kwa mayai kutoka kwa ovari).
Clomid hutumika kusababisha kupata mimba katika wanawake na hali fulani ya matibabu (kama vile tatizo la ovari) kwamba kuzuia zinazotokea kudondoshwa.
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Clomid (clomiphene) er et ikke-steroid fruktbarhet medisin. Det fører til at hypofysen til å frigjøre hormoner for å stimulere eggløsning (frigjøring av et egg fra eggstokken).
Clomid brukes til å forårsake eggløsning hos kvinner med visse medisinske tilstander (slik som polycystisk eggstokk-syndrom) som forhindrer naturlig forekommende eggløsning.
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