Other names for this medication:Acmecilin, Agrocillina, Albipen, Albipenal, Alfasid, Alfasilin, Allégrocine, Alphapen, Alpovex, Ambigel, Ambiopi, Amblosin, Amfipen, Aminoxidin-sulbactam, Amipenix, Amp equine, Ampecu, Ampen, Ampenina, Ampexin, Ampi, Ampibactan, Ampibenza, Ampibex, Ampibos, Ampicaps, Ampicare, Ampicat, Ampicher, Ampicil, Ampicilin, Ampicilinã
The popular medication for many years, “Ampicillin” is an effective antibiotic. Despite the fact that there are new drugs, it is still in demand among physicians and patients. This semisynthetic penicillin antibiotic effective against many bacteria, sepsis, and purulent infection makes it better than others. Not everyone knows exactly from which “Ampicillin” helps, but its low price and availability in pharmacies make it one of the most purchased products. Many patients prescribed it currently own, what to do, of course, should not be. Application “Ampicillin” should be strictly prescribed by a doctor, which takes into account the patient’s health, and particularly his disease. We need to know exactly from what “Ampicillin” helps not to cause the development of superinfection, insensitive to antibiotics.
Characteristics of the drug
This drug belongs to a group of semi-synthetic penicillins and has a broad spectrum of action.
“Ampicillin” tablets used for many years since it is active against most bacteria. Its main active ingredient effectively destroys the cell walls of microorganisms. “Ampicillin” inhibits metabolism in the membranes of cells. Under its influence die many gram-positive and gram-negative bacteria and certain pathogens of intestinal infections. But there are microorganisms that produce a special enzyme beta-lactamase. It destroys penicillin, and the drug is powerless to cure infections caused by bacteria, such as staphylococcus. But he effectively treats a variety of mixed infection, purulent infection and sepsis.
Method of production preparation
1. Previously pills were quite popular “Ampicillin”. Instructions for applying are encouraged to use it in many infections. And now it is fairly common antibiotics. Many patients do buy for different ailments “Ampicillin”. Its price is low, and the drug – one of the most affordable. Although it is not recommended to drink antibiotics without a prescription.
2. In severe infections and is increasingly used in hospitals “Ampicillin” in the form of injections. Putting it intravenously or intramuscularly. The powder was dissolved in a special water for injection.
3. Now the drug is available as a powder for suspension for oral administration. It is more convenient for patients, which is difficult to take a pill, especially children.
How does the drug?
The drug destroys the cells of the bacteria. This leads to their death.
“Ampicillin” is rapidly absorbed into the blood, the maximum plasma concentration observed after a few hours. A by intravenous or intramuscular administration – even earlier. But “Ampicillin” tablets is fairly efficient. After preparation resistant to gastric acid and are not destroyed in the gastrointestinal tract. Within a short time, it accumulates in all body fluids and tissues: penetrates not only in blood, but in the lymph, bile duct, and intra-spinal fluid, bone and skin. Displayed “Ampicillin” with the urine, but also actively allocated with breast milk, so nursing moms do not recommend taking it.
What does the “ampicillin” is used?
It helps the tool in the following diseases:
– bronchitis, pneumonia and even lung abscess;
– Otitis media, sinusitis, tonsillitis and pharyngitis;
– Infections of the kidneys and gall bladder, it is particularly useful in cystitis and urethritis;
– Severe intestinal infections, including typhoid fever and salmonellosis;
– Effective drug against septic wounds, infections of the skin and soft tissues, such as the face or dermatosis, postoperative inflammation;
– It is one of the few drugs that help with gonorrhea, chlamydia and meningitis;
– Treats “Ampicillin” various infections musculoskeletal system, rheumatism, arthritis and osteomyelitis. What does “Ampicillin” appointed yet? Effective when it is listeriosis and cons. It is used as a medicine as a preventive agent for endocarditis – inflammation of the heart muscle.
Unlike other antibiotics penicillin group, this drug is very effective against pyogenic and hemolytic streptococci.
Contraindications to receive
But not all you can drink “Ampicillin” (tablets). Instruction warns against ingestion of those who suffer from the following diseases:
– renal failure or renal disease;
– Hepatic impairment;
– Bronchial asthma;
– Allergic diseases;
– Severe violations of the gastrointestinal tract;
– Mononucleosis or leukemia;
– A tendency to bleeding. You can not take as “Ampicillin” women breastfeeding. Tablet form is not prescribed kids up to 6 years.
Side effects during the medication may cause unwanted symptoms. In this case it is necessary to consult with your doctor about discontinuing the drug. What side effects can cause “Ampicillin”?
– Nausea, vomiting, abdominal pain and dry mouth. Very often develop intestinal dysbiosis.
– Dizziness, drowsiness, trembling hands and feet.
– Headache, seizures.
– Rhinitis or conjunctivitis.
– Body rash, hives and other allergic reactions up to anaphylactic shock.
– Violation of the liver and hepatitis.
– Changing behavior: depression, aggressive or anxiety.
– The tendency to bleeding due to decreased number of platelets in the blood.
– Is reduced as the amount of hemoglobin and white blood cells.
– Often there is the development of fungal infections in patients receiving the drug.
Pills “Ampicillin”: instructions for use, depending on the health status and age of the patient is prescribed 250 mg and 1 g per reception. Drink the medicine should be on an empty stomach with plenty of water. Take “Ampicillin” four times a day at regular intervals of six hours
Usually I drink it half an hour before meals or one hour after. If the drug is taken with food, the absorption of it slows down, respectively, the therapeutic effect decreases. Duration of disease depends. In severe cases it is possible to extend the treatment for 3-4 weeks or even longer. But usually the drug was stopped after a couple of days after the disappearance of symptoms. The solution was “ampicillin” injection can be administered to children in the year, but the treatment is carried out in a hospital. The dose is calculated according to the weight of the child – 50 mg per kilogram. Injections are done less than two weeks and then treatment is continued for adults pills and change the drug to children.
– prescribe drugs only after study sensitivity to microorganisms that caused the disease.
– Strongly contraindicated alcohol intake during treatment.
– In weakened patients may develop superinfection, especially during long-term medication. Bacteria acquire antibiotic sensitivity.
– Simultaneously with the reception “Ampicillin” recommended to drink vitamins and vitamin C, as well as antifungal agents, for example, “Nystatin”.
– Long-term treatment is necessary to monitor the preparation of the kidneys and liver, as well as of the blood, requires regular blood tests.
– If you can not stop improving the state to take “Ampicillin” (tablets). Jeux Guide recommends drinking 2-3 days after symptoms disappear. This is also true for other forms of medicament.
– As with other antibacterial agents “ampicillin” suppresses intestinal microflora and reduce the synthesis of vitamin K. Therefore the desired reception simultaneously with antibiotic drugs dysbacteriosis and vitamin complexes.
– What does “Ampicillin” is now prescribed more often? It is more effective than other antibiotics for purulent wounds, ulcers, abrasions, inflammation of joints and cystitis.
Interaction with other drugs
– Antacids and laxatives, as well as food slows the absorption of the drug and reduce its effect.
– Akorbinovaya acid, on the contrary, accelerate absorption “Ampicillin”.
– Other bactericidal antibiotics enhance the effect of the drug, and bacteriostatic agents – inhibit it.
– NSAIDs diuretics increase and high concentration “Ampicillin” levels, thereby increasing its effect.
– Upon receipt of this antibiotic decreases efficiency estrogensoderjath contraceptives.
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